1) Tumblr: Tumblr is pretty effortless. You can customize everything, from colors, to your theme’s HTML.
2) posterous: Posterous is email blogging at it's best. It's one of the the simplest blogging platforms. It launched in 2008 and has seen some pretty significant increase in usage The platform was created by Sachin Agarwal & Garry Tan.
2) Squarespace: Squarespace is almost completely WYSIWYG (What you see is what you get), in it’s design, interface, and structure. You can drag and drop items from one place to the other with relative ease. You can change your design with just a few clicks. You can even add posts or pages without navigating through a huge administration panel or post editor.
This is one of the few platforms I've seen that comes with a monthly fee. Prices range from $8 for a basic package up to $50 for a community package.
Just a few ideas to throw around before you get started.
